Summary
Bone is the second most frequently replaced tissue, with over four million surgical procedures a year, and tissue engineering offers an alternative to taking grafts from the patient. What it requires is a three-dimensional scaffold that resembles the body's own environment - and bone is highly organised and largely inorganic, so a simple polymer mesh will not do. This study builds hierarchical chitosan/PLA/hydroxyapatite scaffolds doped with TiO2, combining an organic matrix with the inorganic phases that bone tissue actually contains.
Authors & Affiliations
Linari Electrospinning Systems
Linari NanoTech electrospinning system (RT Advanced)
The nanofibres were prepared on a Linari NanoTech system (Pisa, Italy) at two different potentials, 30 and 35 kV - field strengths that require the 60 kV generator of the RT Advanced.