Hybrid Bilayer PLA/Chitosan Nanofibrous Scaffolds Doped with ZnO and Fe3O4

Summary

Full-thickness burns require a transplant, and bioactive materials that promote regeneration are an attractive alternative to taking skin from elsewhere on the patient. This study develops bilayer nanofibrous scaffolds of PLA and chitosan doped with zinc oxide and iron oxide nanoparticles - a two-layer design in which each side can address a different requirement, while the metal oxides contribute antibacterial and magnetic functionality. The scaffolds are conceived to be non-toxic to skin cells while imitating the extracellular matrix.

Authors & Affiliations

• Julia Radwan-Prażłowska Corresponding

  Department of Physical Chemistry, Cracow University of Technology, Poland
• Łukasz Janus

  Department of Physical Chemistry, Cracow University of Technology, Poland
• Marek Piątkowski

  Department of Physical Chemistry, Cracow University of Technology, Poland
• Dariusz Bogdał

  Department of Physical Chemistry, Cracow University of Technology, Poland
• Dalibor Matýsek

  Faculty of Mining and Geology, Technical University of Ostrava, Czech Republic

Linari Electrospinning Systems

Topics

Materials