Impact of Electrospinning Parameters and Post-Treatment Method on Antibacterial and Antifungal Activity of Chitosan Nanofibers

Summary

Chitosan is an obvious candidate for infection-resistant biomaterials thanks to its intrinsic antibacterial activity, and electrospinning processes it with minimal disturbance to its physicochemical properties. The catch is that fabrication parameters and post-processing can significantly alter that biological activity, so they must be tuned rather than assumed. This study prepares chitosan nanofibrous membranes using trifluoroacetic acid and systematically examines how electrospinning parameters and the post-treatment route affect antibacterial and antifungal performance - the practical question for anyone moving chitosan fibres from laboratory to application.

Authors & Affiliations

• Valeriia Korniienko

  Biomedical Research Centre, Sumy State University, Ukraine
• Yevheniia Husak

  Biomedical Research Centre, Sumy State University, Ukraine
• Julia Radwan-Prażłowska

  Department of Biotechnology and Physical Chemistry, Cracow University of Technology, Poland
• Viktoriia Holubnycha

  Biomedical Research Centre, Sumy State University, Ukraine
• Yevhen Samokhin

  Biomedical Research Centre, Sumy State University, Ukraine
• Anna Yanovska

  Biomedical Research Centre, Sumy State University, Ukraine
• Julia Varava

  Biomedical Research Centre, Sumy State University, Ukraine
• Kateryna Diedkova

  Biomedical Research Centre, Sumy State University, Ukraine

Linari Electrospinning Systems

Topics

Materials