Soy protein meets bioactive glass: Electrospun composite fibers for tissue engineering applications

Published in Materials Letters, vol. 199, pp. 143–146 (2017) · Elsevier
DOI: 10.1016/j.matlet.2017.04.042

Summary

Tissue-engineering scaffolds work best when they are both biologically active and made from sustainable, biocompatible materials. This study brings together two such components in a single electrospun fibre: soy protein, an inexpensive, plant-derived biopolymer that supports cell attachment, and bioactive glass, an inorganic material that bonds to bone and stimulates tissue regeneration through the ions it releases. The authors electrospin soy-protein/bioactive-glass composite fibres and characterise the resulting non-woven mats, examining fibre morphology and the incorporation of the glass phase. The fibrous architecture mimics the extracellular matrix while the bioactive glass adds osteo-stimulatory function — a combination aimed at scaffolds for both soft- and hard-tissue engineering, and an example of pairing a natural protein with an inorganic bioactive filler.

Authors & Affiliations

Topics

Tissue Engineering Bioactive Glass Fibers Natural Biopolymers Bone Regeneration

Materials

Soy Protein Isolate Bioactive Glass

Linari Electrospinning Systems

Electrospinning machines by Linari Nanotech
Linari Nanotech designs and manufactures electrospinning systems for nanofiber research and production — including protein/bioceramic composite scaffolds for tissue engineering.
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