Biocompatible Electrospun PCL/Gelatin Nanofibers Loaded with Pinus radiata Bark Extracts

Published in Polymers, vol. 14(12), 2331 (2022) · MDPI · Open access, CC BY
DOI: 10.3390/polym14122331

Summary

Bark from Pinus radiata is a forestry by-product rich in polyphenols, and this study puts it to work inside electrospun poly(ε-caprolactone)/gelatin nanofibres intended for wound healing. Two extract concentrations were compared for their effect on the physicochemical properties of the fibres and on in vitro biocompatibility. All the meshes produced were smooth, uniform and free of beads, indicating that the extract could be incorporated without disturbing fibre formation - the practical obstacle that often defeats natural additives in electrospinning.

Authors & Affiliations

  • Jaime Borges-Vilches
    Laboratory of Biomaterials, Department of Chemical Engineering, University of Concepción, Chile
  • Irem Unalan
    Institute of Biomaterials, University of Erlangen-Nuremberg, Germany
  • Katherina Fernández Corresponding
    Laboratory of Biomaterials, Department of Chemical Engineering, University of Concepción, Chile
  • Aldo R. Boccaccini
    Institute of Biomaterials, University of Erlangen-Nuremberg, Germany

Linari Electrospinning Systems

Linari electrospinning system
The nanofibres were produced on a Linari Engineering S.r.l. system (Pisa, Italy) at an applied voltage of 18 kV - a complete station of the type described on our Starter Kit page, whose control unit is coded HVG-CONT-LCD.

Topics

Wound Healing Natural Extracts Biocompatibility Forestry By-products

Materials

Poly(epsilon-caprolactone) Gelatin Pine bark extract
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