Biocompatible Electrospun Polycaprolactone-Polyaniline Scaffold Treated with Atmospheric Plasma

Published in Bioengineering, vol. 8(2), 24 (2021) · MDPI · Open access, CC BY
DOI: 10.3390/bioengineering8020024

Summary

Conductive polymers can supply electrical cues that encourage tissue growth, and polyaniline is the most studied of them - but it cannot be processed on its own and must be blended with a spinnable partner. This study electrospins a polycaprolactone/polyaniline blend into nanofibres and then treats them with atmospheric plasma, a surface modification that alters wettability and chemistry without touching the bulk. The combination targets scaffolds that are simultaneously conductive, cell-friendly at the surface and mechanically sound.

Authors & Affiliations

  • Maria Licciardello
    Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy
  • Gianluca Ciardelli
    Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy
  • Chiara Tonda-Turo Corresponding
    Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Italy

Linari Electrospinning Systems

Linari electrospinning system, horizontal configuration
The nanofibres were produced on a Linari Engineering S.r.l. system (Pisa, Italy) in horizontal configuration, with the solutions loaded into glass syringes - the arrangement of our Starter Kit, control unit HVG-CONT-LCD.

Topics

Conductive Scaffolds Plasma Surface Treatment Tissue Engineering Wettability

Materials

Polycaprolactone Polyaniline
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