Electrospun PCL/PGS Composite Fibers Incorporating Bioactive Glass Particles

Published in Nanomaterials, vol. 10(5), 978 (2020) · MDPI · Open access, CC BY
DOI: 10.3390/nano10050978

Summary

Poly(glycerol sebacate) and polycaprolactone are both well established for biomedical electrospinning, and their blend has a practical advantage worth noting: it can be processed with benign solvents rather than the aggressive ones the field often relies on. This study examines whether that blend also tolerates the incorporation of bioactive glass particles, producing composite fibres for soft tissue engineering. Keeping the solvent system benign while adding an inorganic bioactive phase is the balance the work sets out to strike.

Authors & Affiliations

  • Marina Luginina
    Dipartimento di Ingegneria Meccanica, Chimica e dei Materiali, University of Cagliari, Italy
  • Katharina Schuhladen
    Institute of Biomaterials, University of Erlangen-Nuremberg, Germany
  • Roberto Orrù
    Dipartimento di Ingegneria Meccanica, Chimica e dei Materiali, University of Cagliari, Italy
  • Giacomo Cao
    Dipartimento di Ingegneria Meccanica, Chimica e dei Materiali, University of Cagliari, Italy
  • Aldo R. Boccaccini
    Institute of Biomaterials, University of Erlangen-Nuremberg, Germany
  • Liliana Liverani Corresponding
    Institute of Biomaterials, University of Erlangen-Nuremberg, Germany

Linari Electrospinning Systems

Linari electrospinning system
The composite fibres were produced on a Linari Engineering S.r.l. system (Valpiana, Grosseto, Italy), with process parameters, temperature and humidity recorded - essential when working with benign solvents, which evaporate differently from conventional ones. See our Starter Kit.

Topics

Soft Tissue Engineering Benign Solvents Bioactive Glass Composites Elastomeric Fibers

Materials

Poly(glycerol sebacate) Polycaprolactone Bioactive glass
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