Electrospun Scaffolds in Periodontal Wound Healing

Summary

Periodontitis is an inflammatory condition of the tissues around the teeth, sustained largely by bacterial infection, and treating it means restoring tissue while controlling bacteria in a confined and awkward space. This study develops biopolymer scaffolds designed to be inserted directly into the periodontal pocket, built by electrospinning with gelatin as the base component combined with other polymers. Placing a nanofibrous structure inside the pocket addresses both goals at once: it supports tissue regeneration and delivers antibacterial action locally.

Authors & Affiliations

• Mária Budai-Szűcs

  Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Hungary
• Marco Ruggeri

  Department of Drug Sciences, University of Pavia, Italy
• Angela Faccendini

  Department of Drug Sciences, University of Pavia, Italy
• Attila Léber

  Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Hungary
• Silvia Rossi

  Department of Drug Sciences, University of Pavia, Italy
• Gábor Varga

  Department of Organic Chemistry, University of Szeged, Hungary
• Maria Cristina Bonferoni

  Department of Drug Sciences, University of Pavia, Italy
• Péter Vályi

  Department of Periodontology, Faculty of Dentistry, University of Szeged, Hungary

Linari Electrospinning Systems

Topics

Materials