Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing

Summary

Chronic wounds are becoming more common as life expectancy rises and diabetes and venous insufficiency spread; ulcers affect around 1% of adults and up to 5% of those over 65, accounting for several percent of total healthcare spending. This study designs electrospun scaffolds made entirely of biopolymers and loaded with two clay minerals, halloysite and montmorillonite, chosen for their ability to support cell adhesion and proliferation. The aim is a dermal substitute that actively accelerates healing rather than simply protecting the wound bed.

Authors & Affiliations

• Giuseppina Sandri Corresponding

  Department of Drug Sciences, University of Pavia, Italy
• Angela Faccendini

  Department of Drug Sciences, University of Pavia, Italy
• Michela Longo

  Department of Drug Sciences, University of Pavia, Italy
• Marco Ruggeri

  Department of Drug Sciences, University of Pavia, Italy
• Silvia Rossi

  Department of Drug Sciences, University of Pavia, Italy
• Maria Cristina Bonferoni

  Department of Drug Sciences, University of Pavia, Italy
• Dalila Miele

  Department of Drug Sciences, University of Pavia, Italy

Linari Electrospinning Systems

Topics

Materials