A New Generation of Electrospun Fibers Containing Bioactive Glass Particles for Wound Healing

Summary

Chitosan is difficult to electrospin alone, so it is blended with poly(ethylene oxide) - and then, to keep the fibres intact in a moist wound, cross-linked. This study uses genipin, a naturally derived cross-linker, and then goes further: bioactive glass particles are incorporated into the chitosan/PEO mats in three different compositions. The aim is a flexible structure that keeps adequate mechanical properties while offering better biological performance than the plain blend, for wound healing applications.

Authors & Affiliations

• Rachele Sergi

  Dipartimento di Ingegneria Enzo Ferrari, University of Modena and Reggio Emilia, Italy
• Valeria Cannillo

  Dipartimento di Ingegneria Enzo Ferrari, University of Modena and Reggio Emilia, Italy
• Aldo R. Boccaccini

  Institute of Biomaterials, University of Erlangen-Nuremberg, Germany
• Liliana Liverani Corresponding

  Institute of Biomaterials, University of Erlangen-Nuremberg, Germany

Linari Electrospinning Systems

Topics

Materials