Shape‐memory properties of degradable electrospun scaffolds based on hollow microfibers

Published in Polymers for Advanced Technologies, vol. 26(12), pp. 1468–1475 (2015) · Wiley
DOI: 10.1002/pat.3630

Summary

Thermo-responsive, degradable shape-memory polymers are of interest in biomedicine as actively moving scaffolds or switchable substrates. Most electrospun shape-memory scaffolds so far have used solid micro- or nanofibres, so this study asks whether scaffolds built from hollow microfibres can be produced from a degradable shape-memory copolyetheresterurethane (PDC) made of crystallizable oligo(p-dioxanone) hard segments and oligo(ε-caprolactone) switching segments. Using coaxial electrospinning, the authors prepared scaffolds whose microfibres all had a similar outer diameter (about 1.4 µm) but different degrees of hollowness — 0%, 13% and 33% — confirmed by scanning electron microscopy. Cyclic thermomechanical tensile tests revealed a pronounced dual-shape effect for every material, and the scaffold with 33% hollowness showed the highest shape-recovery ratio. The work demonstrates that the degree of hollowness, which changes macromolecular chain orientation, is a useful design parameter for tuning both the mechanical and shape-memory behaviour of electrospun shape-memory scaffolds.

Authors & Affiliations

Topics

Shape-Memory Polymers Hollow Microfibers Coaxial Electrospinning Degradable Scaffolds

Materials

Copolyetheresterurethane (PDC) Oligo(p-dioxanone) (OPDO) Oligo(ε-caprolactone) (OCL)

Linari Electrospinning Systems

Coaxial electrospinning needles by Linari Nanotech
Linari Nanotech supplies coaxial electrospinning needles used to produce core–shell and hollow microfibres — such as the degradable shape-memory hollow microfibres in this study.
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