Electrospun PHBHV/Olive Leaf Extract Fiber Meshes

Published in Molecules, vol. 27(19), 6208 (2022) · MDPI · Open access, CC BY
DOI: 10.3390/molecules27196208

Summary

Polyhydroxyalkanoates are biopolyesters produced by microorganisms, biocompatible and biodegradable enough to serve as tissue engineering scaffolds. This study combines one of them, PHBHV, with olive leaf extract - a by-product of the agri-food chain, rich in polyphenols with marked antioxidant activity. Incorporating the extract into electrospun PHBHV fibres yields meshes whose bioactivity comes from what is normally treated as biowaste, an approach that addresses scaffold performance and raw-material sustainability in the same step.

Authors & Affiliations

  • Jose Gustavo De la Ossa
    Cardiovascular Research Laboratory, Department of Surgical Sciences, Italy
  • Serena Danti Corresponding
    Department of Civil and Industrial Engineering, University of Pisa, Italy
  • Jasmine Esposito Salsano
    Doctoral School in Life Sciences, University of Siena, Italy
  • Bahareh Azimi
    Department of Civil and Industrial Engineering, University of Pisa, Italy
  • Veronika Tempesti
    Department of Civil and Industrial Engineering, University of Pisa, Italy
  • Niccoletta Barbani
    Department of Civil and Industrial Engineering, University of Pisa, Italy
  • Maria Digiacomo
    Department of Pharmacy, University of Pisa, Italy
  • Marco Macchia
    Department of Pharmacy, University of Pisa, Italy

Linari Electrospinning Systems

Linari High Voltage generator with Easy Drum
The fibres were spun with a Linari High Voltage generator (Linari Engineering S.r.l., Pisa, Italy) connected to the metal needle, together with the Easy Drum rotary collector. Our high voltage control unit is coded HVG-CONT-LCD.

Topics

Antioxidant Scaffolds Agri-food Biowaste Tissue Engineering Polyphenols

Materials

PHBHV Olive leaf extract
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