Waste Autochthonous Tuscan Olive Leaves as Antioxidant Source for Endothelial Protection

Published in International Journal of Molecular Sciences, vol. 20(23), 5918 (2019) · MDPI · Open access, CC BY
DOI: 10.3390/ijms20235918

Summary

Olive leaves are a by-product of the olive harvest, yet the extract obtained from them is sold as a supplement and an over-the-counter remedy. This in vitro study asks whether extract from the Tuscan cultivar Olivastra seggianese protects endothelial cells against oxidative stress caused by reactive oxygen species - the mechanism implicated in vascular disease. Turning a regional agricultural residue into a documented bioactive material links local biowaste valorisation with cardiovascular research.

Authors & Affiliations

  • Jose Gustavo De la Ossa
    Cardiovascular Research Laboratory, Department of Surgical Sciences, Italy
  • Francesca Felice
    Cardiovascular Research Laboratory, Department of Surgical Sciences, Italy
  • Bahareh Azimi
    Department of Civil and Industrial Engineering, University of Pisa, Italy
  • Jasmine Esposito Salsano
    Doctoral School in Life Sciences, University of Siena, Italy
  • Maria Digiacomo
    Department of Pharmacy, University of Pisa, Italy
  • Marco Macchia
    Department of Pharmacy, University of Pisa, Italy
  • Serena Danti Corresponding
    Department of Civil and Industrial Engineering, University of Pisa, Italy

Linari Electrospinning Systems

Linari High Voltage generator with Easy Drum
A Linari High Voltage generator (Linari Engineering S.r.l., Pisa, Italy) was connected to the metal needle, with the Easy Drum rotary collector - the Starter Kit configuration, control unit HVG-CONT-LCD.

Topics

Oxidative Stress Endothelial Protection Biowaste Valorization Vascular Disease

Materials

Olive leaf extract Polyphenols
Read the full publication
Back to blog